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Jan 16, 2026Open    Access

Rheumatoid Arthritis in Chad: Epidemiological, Clinical and Therapeutic Profile

Harine Abdel Aziz Garba,Adama Bah,Ramadhane Bouchrane,Djikoldinguem Marshall Mouandilmadji,Lienou Vanessa Tagne,Doun Fouda Anne Stéphanie élodie,Abandazegoue-Andjembe Laetitia Cynthia,Zenal Abidine Adoum Hamad,Mahamat Issa Adoum,Sadou Yamoga Lam,Moustapha Niasse,Sa?dou Diallo
Objective: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease. Data from sub-Saharan Africa, particularly Central Africa, remain scarce and diagnosis is often delayed. This study aimed to describe the epidemiological, clinical, biological, radiological, therapeutic, and functional profile of RA in Chad and to situate these findings within the sub-Saharan and international literature. Methods: We conducted a retrospective descriptive study from January 2018 to December 2024 in...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114629


Jan 16, 2026Open    Access

Quantum-Inspired Feature Representations for Depression Subtype Classification: A Synthetic Benchmark Study

Rocco de Filippis,Abdullah Al Foysal
Depression is a clinically heterogeneous disorder comprising subtypes such as melancholic, atypical, anxious, and unspecified, each characterized by distinct symptom profiles and treatment responses. Accurate identification of these subtypes is essential for precision psychiatry and optimizing therapeutic outcomes. This study investigates the potential of quantum-inspired feature representations to enhance the classification of depression subtypes from clinical data. A synthetic dataset of 5000 ...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114448


Jan 16, 2026Open    Access

GenAI Supports the Research on the Key Factors and Intervention Strategies of Mental Health Resilience Construction of Normal School Students

Wendong Chen
As future educators, normal students’ mental health resilience is directly related to the quality of education and teaching and students’ development. With the rapid development of artificial intelligence technology, GenAI provides a new technical path for mental health intervention. Focusing on normal university students, this study explored the key mechanisms and effective intervention strategies of GenAI technology in the cultivation of psychological resilience through mixed research methods....
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114721


Jan 16, 2026Open    Access

Exploring the Future Trends of Digital Advertising in Emerging Markets: Insights from Palestine and Jordan

Hamdi Sadeh
This study examines the evolving dynamics of digital advertising in emerging Middle Eastern markets, with a particular focus on Palestine and Jordan. It identifies key trends shaping the sector, including hyper-personalization and the adoption of immersive technologies such as augmented reality (AR) and virtual reality (VR). Employing a qualitative research design that integrates interviews, focus groups, content analysis, and scenario planning, the study explores the primary forces driving digi...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114800


Jan 16, 2026Open    Access

A Semantic Analysis of “Peach” in Chinese and Japanese

Jiayuan Di
This paper presents a comparative semantic analysis of the concept of “peach” as manifested in Chinese and Japanese four-character idioms and proverbs. Drawing on authoritative lexicographical sources, the study examines both shared and divergent cultural perceptions associated with peaches in the two languages. Guided by theories from cognitive linguistics—specifically metaphor, metonymy, and synecdoche—the paper analyzes the mechanisms through which semantic extensions develop from the core me...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114789


Jan 16, 2026Open    Access

Relearning What Matters: The MELCs as a Crisis Curriculum Reform

Jonalyn C. Malihan
The COVID-19 pandemic disrupted schooling worldwide and forced education systems to reconsider what knowledge and skills are most critical when time, access, and support are limited. In Philippines, the Department of Education responded by introducing the Most Essential Learning Competencies (MELCs), a prioritized set of learning outcomes derived from the K to 12 Curriculum to guide instruction, assessment, and learning material development across flexible learning modalities. This article exami...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114767


Jan 16, 2026Open    Access

Behavioral Supports for ADHD Learners: An Empirical Analysis Informing a Targeted Training Program for Educators

Jonalyn C. Malihan,Erwin B. Marcelo
This study examines the behavioral supports utilized by teachers for learners with attention deficit hyperactivity disorder (ADHD) and analyzes their effectiveness as the empirical basis for developing a targeted training program for educators in selected schools within the Division of Caloocan City during School Year 2022-2023. Employing a descriptive-correlation design, the research involved 50 educators (4 master teachers and 46 regular teachers) chosen through purposeful sampling. Seven beha...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114747


Jan 16, 2026Open    Access

AI-Enhanced Gut Brain Axis Profiling for Major Depressive Disorder: Integrating Synthetic Multi-Omics, Deep Learning, and Interpretable Precision Therapeutics

Rocco de Filippis,Abdullah Al Foysal
Major depressive disorder (MDD) has been repeatedly linked to disruptions of the gut brain axis (GBA), yet practical decision systems that convert multi-omics patterns into patient-specific guidance remain limited. We present an end-to-end, explainable pipeline that learns putative GBA signatures of MDD from synthetic data and translates model attributions into hypothesis-driven nutritional and pharmacological suggestions. We simulated a cohort of N = 1,500 individuals (30% MDD) comprising 200 m...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114444


Jan 15, 2026Open    Access

Real-Time Cyber Monitoring and Threat Detection System with Hybrid AI Analysis

Ashley Audrey Innocent Yanguema,Chunyong Yin
Modern Security Operations Centers (SOCs) face the dual challenge of identifying zero-day threats in high-throughput network streams and mitigating analyst alert fatigue. This paper proposes Sentinel AI, a hybrid detection framework orchestrating unsupervised statistical learning with Large Language Model (LLM) reasoning. We introduce a novel dual-engine architecture: a low-latency Isolation Forest model for real-time anomaly filtration (  complexity), and a semantic analysis engine utilizi...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114742


Jan 15, 2026Open    Access

Weighted Stuffed Animals and Dental Anxiety in Pediatric Patients: A Randomized Controlled Trial

Hussain Alfailkawi,Cheen Loo,Gerald Swee,Miranda Boynton,Sarah Pagni
Background: Dental anxiety is a common barrier to effective care in pediatric patients. Deep touch pressure (DTP) interventions, such as weighted sensory tools, have demonstrated calming effects in various clinical settings, but their role in pediatric dentistry remains underexplored. Methods: This randomized controlled trial evaluated the effect of a weighted stuffed animal on anxiety and behavior in children aged 4 to 14 years receiving restorative dental trea...
Open Access Library J.   Vol.13, 2026
Doi:10.4236/oalib.1114724


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