Evaluation of the Effectiveness of Urine Dipstick in the Screening of Urinary Infection in Relation to the Reference Method: The Cytobacteriological Examination of Urine
The cytobacteriological
examination of urine is a biological test most commonly asked in the hospital.
The results of a large part of urinary sample analyzed are negative,
representing a heavy workload for bacteriology laboratories, burden that we
would like to limit. In this context the aim of our study was to evaluate a
screening test for urinary tract infection by urine dipstick compared to the
reference method; the cytobacteriological examination of urine finally promotes the realization of the urine dipstick before any
urine culture. We selected 600 patients whom the physician asked the
cytobacteriological examination of urine, and on every patient, we proceeded to
urine collection and finally
realized the urine dipstick before urine culture; two
parameters on urine dipstick have helped us to confirm the negativity and
positivity of the dipstick, its leukocytes and nitrites. The results of urine
dipstick are positive if one or less of the two tests, leukocyte and nitrite is
positive; the result is negative if both tests are negative.
The urine culture was done on cled agar and bacterial identification was made
on cultural characteristics, biochemical (API 2OE gallery of biomerieux). The
results of urine culture were collected 72 hours after culture. For the
analysis of results, the sensitivity, specificity, predictive values (positive
predictive value and negative predictive value), the youden index, the
proportion of correctly-classified subjects and the likelihood ratio (positive
likelihood ratio and negative likelihood ratio) were calculated. The urine
dipstick has the sensitivity of 96%, specificity of 90%, the positive
predictive value of 74%, the negative predictive value of 98.8%, youden index
of 0.86, the proportion of subjects correctly classified of 91.6%, a positive
likelihood ratio of 9.6 and a negative likelihood ratio of 0.04. In the light of these results, the urine dipstick is
an elimination test, by its very high sensitivity (96%), its high negative
predictive value (98.8%) and negative likelihood ratio close to 0 or 0.04, and if the dipstick does not detect nitrite and
leukocyte, the diagnosis of urinary tract infection is highly unlikely (<2%
probability).
Cite this paper
Bakadia, B. M. , Babidi, B. L. , Mutoba, T. F. , Mbang, M. P. , Ndaya, K. A. , Biampata, M. J. and Kasamba, I. E. (2018). Evaluation of the Effectiveness of Urine Dipstick in the Screening of Urinary Infection in Relation to the Reference Method: The Cytobacteriological Examination of Urine. Open Access Library Journal, 5, e4790. doi: http://dx.doi.org/10.4236/oalib.1104790.
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