Heavy Metals Exposure on Urbanized and Industrial polluted territories and Effects on Functional State of Systems of different cohorts of population in Crimean region of Ukraine

On urbanized and industrial territories in Crimean region of Ukraine with exceedances of critical loads for heavy metals (HM) different cohorts of population were examined. Content of toxic HM (Hg, Pb, Cd, Ni) in hair of healthy children and adult mainly did not exceeded, but level of essential HM (Fe, Zn, Cu, Mn) frequently was decreased. The differences of HM content in some special cohorts (mental retardation, autonomic nervous system dysfunction, sportsman) was revealed. Content of HM in 375 samples of venous and umbilical cord blood, placenta, breast milk of puerperants and their new-born children strongly varied. Correlation analysis by Spearman and multiple regression analysis shown not so close but statistically significant relationships between levels of HM and functional state of central and autonomic nervous, immune and cardio-vascular systems, their different sensitivity to different HM in distinct cohorts of population.