%0 Journal Article
%T Correlation between hCG Kinetics and the Effectiveness of Methotrexate in the Management of Ectopic Pregnancies
%A Oum Elkheir Soltana Senouci
%A Fadl-Allah Aboubekr
%A Hind Bedjaoui
%A Mimouna Messaoud
%A Ikram Tachema
%J Open Access Library Journal
%V 13
%N 1
%P 1-7
%@ 2333-9721
%D 2026
%I Open Access Library
%R 10.4236/oalib.1114676
%X <strong>Purpose:</strong> To evaluate a therapeutic monitoring strategy for ectopic pregnancies treated with methotrexate (MTX) injection based on hCG level kinetics, in order to identify patients at low risk of treatment failure. <strong>Materials and Methods:</strong> This series of 14 cases allowed us to evaluate the success rate of therapeutic management with a single injection of methotrexate (MTX), based on the kinetics of hCG levels. The protocol stipulated that if the decrease was greater than 20% between days 1 and 4, follow-up was limited to an hCG measurement one month later. <strong>Results:</strong> Among the 14 patients treated, the overall success rate of MTX treatment was 85.71%. <strong>Conclusion:</strong> Our protocol allows us to select patients at low risk of failure of single-dose MTX treatment, and to offer them less restrictive monitoring.<br />
%K Methotrexate
%K Ectopic Pregnancy
%K hCG
%U http://www.oalib.com/paper/6881779